Study and Synthesis of Biologically Active Phenothiazines,their Sulfones,and Ribofuranosides |
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| Authors: | Nishidha Khandelwal Abhilasha Yadav Naveen Gautam D. C. Gautam |
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| Affiliation: | Department of Chemistry , University of Rajasthan , JLN Marg, Jaipur , India |
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| Abstract: | The present article describes the synthesis of new 10H-phenothiazines using the Smiles rearrangement. These synthesized phenothiazines on oxidation with 30% hydrogen peroxide in glacial acetic acid yield sulfones, and when treated with sugar give ribofuranosides. These compounds are evaluated for their anthelmintic and antimicrobial activities. The structural assignment of the synthesized compounds is made on the basis of elemental analysis and spectroscopic data. |
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| Keywords: | Smiles rearrangement sulfones ribofuranosides anthelmintic activities antimicrobial activities |
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