Synthesis of [bis(Inosine-5′)]-tetraphosphate and [bis(Inosine-5′)]-pentaphosphate Analogues Bearing the Residues of Methylenediphosphonic Acid |
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| Authors: | A V Shipitsyn N B Tarussova E A Shirokova A A Krayevsky |
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| Institution: | Engelhardt Institute of Molecular Biology, Russian Academy of Sciences , 32 Vavilov str., Moscow, 117984, Russia |
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| Abstract: | Abstract Various methods of synthesis of metabolically stable phosphonate analogues of bisnucleoside oligophosphates containing two residues of methylenediphosphonic acid in the oligophosphate chain are studied. Phosphonate analogues of Ip4I and Ip5I are prepared. |
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