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Synthesis and in vitro leishmanicidal activity of some hydrazides and their analogues |
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| Authors: | Khan Khalid Mohammad Rasheed Maimona Zia-Ullah Hayat Safdar Kaukab Farhana Choudhary M Iqbal Atta-ur-Rahman Perveen Shahnaz |
| Institution: | International Center for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, -75270, Karachi, Pakistan. hassaan2@super.net.pk |
| Abstract: | Twenty-one hydrazides were synthesized by treating different esters with hydrazine hydrate. Substituted hydrazides were obtained by treating hydrazides with alkyl/aryl/acyl halides. Some of these compounds exhibit potential in vitro leishmanicidal activity. The structures of all the synthesized compounds were confirmed by spectroscopic analysis. |
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