鼻腔鼻窦淋巴瘤相关因素及临床特征研究

目的：探讨早期鼻腔鼻窦淋巴瘤（NHL）相关因素及临床特征。方法：对经我院病理确诊为鼻腔鼻窦NHL的患者及来自同期收治的慢性鼻．鼻窦炎病例各28例，进行回顾性对照研究。统计分析应用SPSS17．0统计软件进行。结果：28例鼻腔鼻窦NHL中，NKfr细胞淋巴瘤18例，外周T细胞淋巴瘤7例，B细胞淋巴瘤3例。统计分析显示，对药物（麻黄素、肾上腺素）收缩反应差OR28．140（1．995．396．972）、发热OR99．366（0．752—13130．619）、粘膜不光滑OR34．665（1．464—820．575）、下鼻甲质地硬oR25．797（1．395-447．001）是鼻腔鼻窦NHL的高危指标。结论：对药物（麻黄素、肾上腺素）收缩反应差、发热、粘膜不光滑、下鼻甲质地硬是早期鼻腔鼻窦淋巴瘤的强危险信号和重要的诊断线索。

Research of Relevant Factors and Clinical Features on Sinonasal Lymphoma

Objective： To Investigate the Relevant factors and clinical features on Sinonasal lymphoma （NHL）. Methods： Each 28 cases of diagnosed asnasal cavit from our hospital and paranasal sinuses in patients with NHL and ehronicnasal-sinusitisdisease from the same period were retrospective controlled studied. SPSS 17.0 statistical software was applied for statistical analysis. Re, suits： In 28 patients with sinonasal NHL, 18 cases ofNK / T celllymphoma, 7 eases of peripheral T-cell lymphoma and 3 cases of B-cell lyrnphoma.statistical analysis indicated that： poor contractile response to drugs （ephedrine,epinephrine）OR was 28.140 （1.995-396,972）, the fever OR was 99.366（0.752-13130.619）, the non-smooth mucous membrane OR was 34.665 （ 1.464-820.575） and hard texture of the inferior turbinate OR was 25.797 （1.395-447.001）, and they were the high-risk indicators of sinonasal lymphoma （NHL）. Conclusion： poor contractile response to drugs （ephedrine,epinephrine）, the fever, the non- smooth mucous membrane and hard texture of the inferior turbinate are strong danger signals and important diagnostic clues of Sinonasal lymphoma.