Evolution by leaps: gene duplication in bacteria |
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| Authors: | Margrethe H Serres Alastair RW Kerr Thomas J McCormack Monica Riley |
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| Affiliation: | (1) Marine Biological Laboratory, Josephine Bay Paul Center, Woods Hole, MA 02543, USA;(2) Wellcome Trust Centre for Cell Biology, University of Edinburgh, Kings Buildings, Mayfield Road, Edinburgh, EH9 3JR, UK;(3) Laboratory of Neurobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA;(4) Marine Biological Laboratory, Josephine Bay Paul Center, Woods Hole, MA 02543, USA |
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| Abstract: | Background Sequence related families of genes and proteins are common in bacterial genomes. In Escherichia coli they constitute over half of the genome. The presence of families and superfamilies of proteins suggest a history of gene duplication and divergence during evolution. Genome encoded protein families, their size and functional composition, reflect metabolic potentials of the organisms they are found in. Comparing protein families of different organisms give insight into functional differences and similarities. |
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