A synthetic peptide with morphine-like pharmacologic action. |
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Authors: | A Goldstein J S Goldstein B M Cox |
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Affiliation: | Addiction Research Foundation, Palo Alto, California 94304, USA |
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Abstract: | On purely theoretical grounds an oligopeptide was synthesized, which produced typical morphine-like effects on the guinea pig myenteric plexus-longitudinal muscle preparation and in the opiate receptor binding assay. It is a linear heptapeptide with structure HTyrGlyGlyLysMetGlyOH. This is the first opioid peptide of known structure. |
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