B-lymphocyte-induced maturation protein-1 (Blimp-1) gene of torafugu (Takifugu rubripes) |
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Authors: | Ohtani Maki Miyadai Toshiaki Hiroishi Shingo |
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Institution: | Research Center for Marine Bioresources, Faculty of Biotechnology, Fukui Prefectural University, 49-8-2 Katsumi, Obama, Fukui, 917-0116, Japan. |
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Abstract: | Homologous gene of B-lymphocyte-induced maturation protein-1 (Blimp-1) of torafugu (Takifugu rubripes) was identified by tblast search analysis. RT-PCR and 5'RACE clearly defined the sequence of the UTR and coding region which has been ambiguously determined by tblast analysis. Fugu Blimp-1 was mainly expressed in the lymphoid organs. These finding imply that Blimp-1 would take a major role in the terminal differentiation of B-cells to plasma cells in fish. |
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