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Secondary Metabolites from Marine Micromonospora: Chemistry and Bioactivities
Authors:Sisi Qi  Min Gui  Huanhuan Li  Chunbo Yu  Hongji Li  Zheling Zeng  Peng Sun
Abstract:Marine Micromonospora was revealed to be a rather untapped and a rich source of chemically diverse and unique bioactive natural products. This review is aimed to make a comprehensive survey of secondary metabolites that were derived from marine Micromonospora including chemical diversity and biological activities. A total of 116 compounds from 41 marine Micromonospora species have been reported, covering the literatures from 1997 to 2019. These compounds contain several structural classes such as polyketides (PKS), nonribosomal peptides (NRPS), PKS‐NRPS hybrids, terpenes and others, and they present cytotoxic, antibacterial, antiparasitic, chemopreventive or antioxidant activities.
Keywords:marine Micromonospora  secondary metabolites  natural products  biological activity  polyketide
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