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Colletoindole A from the Mangrove Plant Endophytic Fungus Colletotrichum tropicale SCSIO 41022
Authors:Xiuping Lin  Wen Ai  Meng Li  Xiaoyan Pang  Zhiran Ju  Da Guan  Bin Yang  Xuefeng Zhou  Junfeng Wang  Juan Liu  Lishu Wang  Yonghong Liu
Abstract:A new indole derivative colletoindole A ( 1 ), along with two new indole derivatives ( 2 and 3 ) and one known compound acropyrone ( 4 ) were isolated from cultures of Colletotrichum tropicale SCSIO 41022 derived from a mangrove plant Kandelia candel. The structures of 1 – 4 were determined by analysis of NMR and MS data. The cytotoxicity of 1 , 2 and 4 , and the COX‐2 inhibitory activity of 1 and 2 were evaluated.
Keywords:mangrove plant  endophytic fungus  indole derivative  cytotoxicity  biological activity
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