| Affiliation: | 1.Department of Microbiology, University of Massachusetts, Amherst, MA, USA;2.Institute for Cellular Engineering, University of Massachusetts, Amherst, MA, USA
3.Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA, USA;4.Joint Genome Institute, Walnut Creek, CA, USA;5.Department of Biology, University of Massachusetts, Amherst, MA, USA;6.Graduate Program in Organismal and Evolutionary Biology, University of Massachusetts, Amherst, MA, USA. |
| Abstract: | Clostridium indolis DSM 755T is a bacterium commonly found in soils and the feces of birds and mammals. Despite its prevalence, little is known about the ecology or physiology of this species. However, close relatives, C. saccharolyticum and C. hathewayi, have demonstrated interesting metabolic potentials related to plant degradation and human health. The genome of C. indolis DSM 755T reveals an abundance of genes in functional groups associated with the transport and utilization of carbohydrates, as well as citrate, lactate, and aromatics. Ecologically relevant gene clusters related to nitrogen fixation and a unique type of bacterial microcompartment, the CoAT BMC, are also detected. Our genome analysis suggests hypotheses to be tested in future culture based work to better understand the physiology of this poorly described species. |
