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Glucocorticoids decrease the bioavailability of TGF-beta which leads to a reduced TGF-beta signaling in hepatic stellate cells
Authors:Bolkenius Ursula  Hahn Daniela  Gressner Axel M  Breitkopf Katja  Dooley Steven  Wickert Lucia
Affiliation:a Institute of Clinical Chemistry and Pathobiochemistry, RWTH University Hospital Aachen, Pauwelsstr. 30, D-52074 Aachen, Germany
b Molecular Alcohol Research in Gasteroenterology, Department of Medicine II, University Hospital Mannheim, University Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany
Abstract:
Keywords:Corticosteroid   Glucocorticoid receptor   Smad   Hepatic stellate cells   TGF-β
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