Adenosine 3', 5'-monophosphate in mycobacteria. |
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Authors: | H Padh T A Venkitasubramanian |
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Institution: | Department of Biochemistry Vallabhbhai Patel Chest Institute University of Delhi Delhi-110007 India |
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Abstract: | Cyclic adenosine 3′,5′-monophosphate (cyclic AMP) is present in saprophytic fast growing as well as pathogenic and non-pathogenic slow growing mycobacteria. Apparently there does not seem to be any direct relationship between either intra- or extra-cellular cyclic AMP content with the growth rate of the bacteria. Intracellular cyclic AMP content is much higher than that of . grown on a similar carbon source. Glucose when added to the cells suspended in phosphate buffer lowers the intracellular cyclic AMP content by 6–8 fold. |
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