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Investigation of PGM13, PGM16, and PGM17 variants by isoelectric focussing. Evidence for new subtypes of the PGM 1 3 and PGM 1 7 alleles
Authors:M I Kamboh  R L Kirk
Institution:(1) Department of Human Biology, John Curtin School of Medical Research, Box 334, Canberra City, Australia
Abstract:Summary A total of 345 haemolysates previously phenotyped by starch gel electrophoresis and known to contain the products of the PGM 1 3 , PGM 1 6 , and PGM 1 7 alleles have been analyzed by thin layer polyacrylamide gel isoelectric focussing in the pH range 5–7. Two common subtypes, 3+and 3-, of the PGM 1 3 allele have been found in a number of Pacific populations. A single form of the PGM 1 7 allele was observed in the Western Caroline Islands. In contrast, one of two Indian PGM17 variants focussed to a different position when compared with the form found at polymorphic frequency in the Western Caroline Islands. Only one type of the PGM 1 6 allele was detected during the present investigation.
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