Relation between mouth and haematogenous infection in total joint replacements. |
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Authors: | C. A. Bartzokas R. Johnson M. Jane M. V. Martin P. K. Pearce Y. Saw |
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Affiliation: | Wirral Hospital NHS Trust, Wirral, Merseyside. |
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Abstract: | OBJECTIVE--To investigate the source of infections associated with orthopaedic prostheses. DESIGN--Analysis of four infections of prosthetic joints with case records; minimum inhibitory and minimum bactericidal concentrations and sodium dodecylsulphate polyacrylamide gel electrophoresis of the cell wall polypeptides of the Streptococcus sanguis isolates from the mouth and infected prostheses; examination of the patients'' mouths for periodontal disease and caries. SUBJECTS--Four adults (three men) aged 58-83. RESULTS--For each patient the strain of S sanguis isolated from the mouth was indistinguishable from that isolated from the prosthesis. All patients had severe periodontal disease and caries. CONCLUSIONS--The mouth was probably the source of bacterial infection in the prosthetic joints of these patients; the route of infection was possibly haematogenous. Incipient oral infection should be treated before joint replacement, and oral health should be maintained indefinitely. |
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