Trace Elements in the Hair of Hemodialysis Patients |
| |
Authors: | Akinobu Ochi Eiji Ishimura Yoshihiro Tsujimoto Ryusuke Kakiya Tsutomu Tabata Katsuhito Mori Tetsuo Shoji Hiroshi Yasuda Yoshiki Nishizawa Masaaki Inaba |
| |
Institution: | (1) Department of Nephrology, Metabolism, Endocrinology, and Molecular Medicine, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan;(2) Inoue Hospital, 16-17, Enoki-chou, Suita, Osaka 564-0053, Japan;(3) Research Laboratory, La Bell Vie Inc., 8-4, Nihonbashi-Tomizawachou, Chuo-ku, Tokyo 103-0006, Japan; |
| |
Abstract: | Trace element disturbance is often observed in hemodialysis patients. While trace element concentrations have been reported
in blood samples from hemodialysis patients, they have not been well investigated in scalp hair. In the present study, 22
trace elemental concentrations were measured by inductively coupled plasma-atomic emission spectrometry in the scalp hair
of 80 male hemodialysis patients and compared with those of 100 healthy male subjects. In hemodialysis patients, the concentrations
of beryllium, arsenic, magnesium, chromium, manganese, iron, selenium, molybdenum, iodine, vanadium, and cobalt were significantly
higher than those in healthy subjects, while lead, mercury, copper, germanium, and bromine were significantly lower than those
in the former group. No significant differences were observed for lithium, aluminum, cadmium, zinc, boron, or nickel. There
were significant positive correlations between the duration of hemodialysis and the magnesium and manganese concentrations.
There was a significant negative correlation between cadmium concentration and the duration of hemodialysis. There were significant
positive correlations between dialysis efficacy (Kt/V) and magnesium, manganese, zinc, and selenium concentrations. In conclusion,
trace element concentrations of the scalp hair are different between hemodialysis patients and healthy subjects. Essential
trace elements, such as magnesium, manganese, zinc, and selenium, may be affected by the duration of hemodialysis and Kt/V. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|