Cumulative radiation dose estimates from medical imaging in paediatric patients with non-oncologic chronic illnesses. A systematic review |
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| Affiliation: | 1. Medical Physics Department, University Hospital “Maggiore della Carità”, Novara, Italy;2. Nephrology Department, University Hospital “Maggiore della Carità”, Novara, Italy;3. Nuclear Medicine Department, University Hospital “Maggiore della Carità”, Novara, Italy;4. Radiology Department, University Hospital “Maggiore della Carità”, Novara, Italy;5. Istituto Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Pisa, Italy;1. Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Canada;2. Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada;1. Yale School of Medicine, New Haven, Connecticut;2. Yale Cancer Center, New Haven, Connecticut;3. Cancer Outcomes, Public Policy, and Effectiveness Research Center at Yale, New Haven, Connecticut;4. Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut;5. Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey;1. Department of Radiology, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA, USA;2. Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA;1. Section of Environment and Radiation, International Agency for Research on Cancer, Lyon, France;2. Department of Radiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;3. Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina |
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| Abstract: | Paediatric patients with non-oncologic chronic illnesses often require ongoing care that may result in repeated imaging and exposure to ionizing radiation from both diagnostic and interventional procedures. In this study the scientific literature on cumulative effective dose (CED) of radiation accrued from medical imaging among specific cohorts of paediatric, non-oncologic chronic patients (inflammatory bowel disease, cystic fibrosis, congenital heart disease, shunt-treated hydrocephalus, hemophilia, spinal dysraphism) was systematically reviewed.We conducted PubMed/Medline, Scopus and EMBASE searches of peer-reviewed papers on CED from diagnostic and therapeutic radiological examinations. No time restriction was introduced in the search. Only studies reporting CEDs accrued for a period >1 year were included.We found that the annual CED was relatively low (<3 mSv/year) in cystic fibrosis, congenital heart disease, patients with cerebrospinal fluid shunts and hemophilia, while being moderate (>3–20 mSv/year) in Crohn's patients.This extra yearly radiation exposure accrues over the lifetime and can reach high values (>100 mSv) in selected cohorts of paediatric chronic patients. |
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| Keywords: | Radiation Dose Paediatric Chronic disease |
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