Efficacy of silver-releasing rubber for the prevention of Pseudomonas aeruginosa biofilm formation in water |
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Authors: | De Prijck Kristof Nelis Hans Coenye Tom |
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Institution: | Laboratorium voor Farmaceutische Microbiologie, Universiteit Gent, Gent, Belgium. |
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Abstract: | The aim of the present study was to evaluate the efficacy of Elastoguard silver-releasing rubber in preventing Pseudomonas aeruginosa biofilm formation in water. Biofilm formation by P. aeruginosa under various conditions in an in vitro model system was compared for silver-releasing and conventional rubber. Under most conditions tested, the numbers of sessile cells attached to silver-releasing rubber were considerably lower with reference to conventional rubber, although the effect diminished with increasing volumes. The release of silver also resulted in a decrease in planktonic cells. By exposing both materials simultaneously to conditions for biofilm growth, it became obvious that the antibiofilm effect was due to a reduction in the number of planktonic cells, rather than to contact-dependent killing of sessile cells. The data demonstrate that the use of silver-releasing rubber reduces P. aeruginosa biofilm in water and reduces the number of planktonic cells present in the surrounding solution. |
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