| 慢性低O_2高CO_2大鼠肺肥大细胞对肺小动脉的作用 |
| |
| 引用本文： | 林升,王良兴,徐正衸,龚永生,方周溪.慢性低O_2高CO_2大鼠肺肥大细胞对肺小动脉的作用[J].中国应用生理学杂志,2000(3). |
| |
| 作者姓名： | 林升 王良兴 徐正衸 龚永生 方周溪 |
| |
| 作者单位： | 浙江省温州医学院病理解剖教研室!温州325003(林升)，温州医学院肺心病研究室(王良兴，徐正衸，龚永生)，温州医学院电镜室(方周溪) |
| |
| 基金项目： | 浙江省自然科学基金!资助项目 (3985 30 )，温州市科委资助!项目 (KW 96 0 0 0 5 ) |
| |
| 摘 要： | 目的 :探讨慢性低O2 高CO2 大鼠肺肥大细胞 (MC)对肺小动脉的作用。方法 :采用慢性低O2 高CO2 肺动脉高压模型 ,观察大鼠肺MC和肺小动脉形态改变及测定肺动脉压。结果 :观察到大鼠肺动脉压力升高和肺MC脱颗粒及空泡变。结论 :肺MC可能也是肺动脉高压形成的因素之一。
|
| 关 键 词： | 低O2 高CO2 肺动脉 肺MC |
EFFECTS OF THE MAST CELL ON THE PULMONARY ARTERY IN PULMONARY HYPERTENSION RATS INDUCED BY HYPOXIA AND HYPERCAPNIA |
| |
| YU Ling-sheng,WANG Liang-xing,XU Zheng-Jie.EFFECTS OF THE MAST CELL ON THE PULMONARY ARTERY IN PULMONARY HYPERTENSION RATS INDUCED BY HYPOXIA AND HYPERCAPNIA[J].Chinese Journal of Applied Physiology,2000(3). |
| |
| Authors: | YU Ling-sheng WANG Liang-xing XU Zheng-Jie |
| |
| Abstract: | Aim: To study effects of the mast cell on the pulmonary artery in pulmonary hypertension rats induced by hypoxia and hypercapnia. Methods: In pulmonary hypertension rats induced by chronic hypoxia and hypercapnia,the MC and the PA were observed and the mPAP were measured.Results:The MC showed degranulation and vacuolar degeneration. The fibroblast showed proliferation:The mPAP were increaded.Conclusion:The MC is one of possible factor to increase pulmonary hypertension. |
| |
| Keywords: | hypoxia hypercapnia mast cell pulmonary artery |
| 本文献已被 CNKI 等数据库收录！ |
