A benchmark for statistical microarray data analysis that preserves actual biological and technical variance |
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Authors: | Benoît De Hertogh Bertrand De Meulder Fabrice Berger Michael Pierre Eric Bareke Anthoula Gaigneaux Eric Depiereux |
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Affiliation: | 1.Unité de Recherche en Biologie Moléculaire,Facultés Universitaires Notre-Dame de la Paix (F.U.N.D.P.),Belgium |
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Abstract: | Background Recent reanalysis of spike-in datasets underscored the need for new and more accurate benchmark datasets for statistical microarray analysis. We present here a fresh method using biologically-relevant data to evaluate the performance of statistical methods. |
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