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Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability
Authors:Benjamin E. L. Lauffer  Robert Mintzer  Rina Fong  Susmith Mukund  Christine Tam  Inna Zilberleyb  Birgit Flicke  Allegra Ritscher  Grazyna Fedorowicz  Roxanne Vallero  Daniel F. Ortwine  Janet Gunzner  Zora Modrusan  Lars Neumann  Christopher M. Koth  Patrick J. Lupardus  Joshua S. Kaminker  Christopher E. Heise  Pascal Steiner
Abstract:
Keywords:Cell Cycle   Cell Death   Crystallography   Gene Expression   Histone Deacetylase   Histone Deacetylase Inhibitors   Histone Modification   Binding Kinetics
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