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No Proof of HTLV-I/II in Intravenous Drug Abusers with a High Rate of HIV-1 Infection in Central Thailand
Authors:Suranga Saguanwongse  Amorntip Muangpom  Nuangjun Ruchusatsawat  Suthon Wongcheree  Paijit Warachit  Kikuko Miyamura  Shudo Yamazaki  Mitsuo Honda
Abstract:Serum specimens of 1,074 intravenous drug abusers (IVDA) were examined for infection with HIV-1, HTLV-I and HTLV-II in central Thailand. Three hundred and sixty-two of the specimens were seropositive for HIV-1 (33.7%). The HIV-1 seropositive IVDAs exhibited increased seropositivity with age through group 40–44 and significantly decreased seropositivity over the age of 45. In contrast, no seropositivity to either HTLV-I or -II was detected in the samples tested by a particle-agglutination assay for HTLV followed by type-specific Western blotting for HTLV. Reference to previous reports suggested that the rate of HIV infection in IVDAs has decreased with no HTLV-I or HTLV-II in Thailand when compared with that of the HIV infection in 1992.
Keywords:intravenous drug abusers  HIV-1  HTLV-I  HTLV-II  thailand
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