The Chemical Diversity of Lantana camara: Analyses of Essential Oil Samples from Cuba,Nepal, and Yemen |
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| Authors: | Prabodh Satyal Rebecca A. Crouch Lianet Monzote Paul Cos Nasser A. Awadh Ali Mehdi A. Alhaj William N. Setzer |
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| Affiliation: | 1. Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL, USA;2. Parasitology Department, Institute of Tropical Medicine ‘Pedro Kouri’, Havana, Cuba;3. Laboratory for Microbiology, Parasitology and Hygiene, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Antwerp University, Universiteitsplein 1, B‐2610, Antwerp, Belgium;4. Pharmacognosy Department, Faculty of Clinical Pharmacy, Albaha University, Al Baha, Kingdom of Saudi Arabia;5. Pharmacognosy Department, Faculty of Pharmacy, Sana'a University, Sana'a, Yemen;6. Pharmacognosy Department, Faculty of Pharmacy, Aden University, Aden, Yemen |
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| Abstract: | The aerial parts of Lantana camara L. were collected from three different geographical locations: Artemisa (Cuba), Biratnagar (Nepal), and Sana'a (Yemen). The essential oils were obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry. A cluster analysis of 39 L. camara essential oil compositions revealed eight major chemotypes: β‐caryophyllene, germacrene D, ar‐curcumene/zingiberene, γ‐curcumen‐15‐al/epi‐β‐bisabolol, (E)‐nerolidol, davanone, eugenol/alloaromadendrene, and carvone. The sample from Cuba falls into the group dominated by (E)‐nerolidol, the sample from Nepal is a davanone chemotype, and the sample from Yemen belongs to the β‐caryophyllene chemotype. The chemical composition of L. camara oil plays a role in the biological activity; the β‐caryophyllene and (E)‐nerolidol chemotypes showed antimicrobial and cytotoxic activities. |
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| Keywords: | Essential oils Cluster analysis Chemotaxonomy Antimicrobial activity Cytotoxic activity |
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