The Adaptive Evolution Database (TAED) |
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| Authors: | David A Liberles David R Schreiber Sridhar Govindarajan Stephen G Chamberlin Steven A Benner |
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| Affiliation: | (1) Department of Chemistry, University of Florida, Gainesville, FL 32611, USA;(2) Department of Anatomy and Cell Biology, University of Florida, Gainesville, FL 32611, USA;(3) Bioinformatics Division, EraGen Biosciences, 12085 Research Drive, Alachua, FL 32615, USA;(4) Department of Biochemistry and Biophysics and Stockholm Bioinformatics Center, Stockholm University, 10691 Stockholm, Sweden;(5) Maxygen, 515 Galveston Drive, Redwood City, CA 94063, USA |
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| Abstract: | Background Developing an understanding of the molecular basis for the divergence of species lies at the heart of biology. The Adaptive Evolution Database (TAED) serves as a starting point to link events that occur at the same time in the evolutionary history (tree of life) of species, based upon coding sequence evolution analyzed with the Master Catalog. The Master Catalog is a collection of evolutionary models, including multiple sequence alignments, phylogenetic trees, and reconstructed ancestral sequences, for all independently evolving protein sequence modules encoded by genes in GenBank [1]. |
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