Autogenous regulation of the synthesis of ribosomal proteins, L10 and L7/12, in Escherichia coli

Summary The in vitro synthesis of Escherichia coli ribosomal proteins, L10 and L7/12, is specifically repressed by the addition of the L10-L7/12 complex, while that of other ribosomal proteins encoded by the neighboring operons is not affected. Thus the expression of the rpoBC operon is controlled by two autorepression systems, one for the two ribosomal proteins and the other for RNA polymerase and subunits, both operating probably at the translational level.