Fast atom bombardment: A new mass spectrometric method for peptide sequence analysis |
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| Authors: | Howard R Morris Maria Panico Michael Barber Robert S Bordoli Robert D Sedgwick Andrew Tyler |
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| Institution: | Department of Biochemistry, Imperial College of Science and Technology, London. S.W.7. U.K.;Department of Chemistry, University of Manchester, Institute of Science and Technology, Manchester, U.K. |
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| Abstract: | We have studied a selection of peptides using a new mass spectrometric ionisation technique - fast atom bombardment (FAB). We define the fragmentation pathways observed and comment on the utility in sequence analysis. A simple acetylation experiment is shown to aid rapid sequence assignment. |
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| Keywords: | FAB Fast atom bombardment |
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