On the biosynthesis of biotin in Achromobacter IVSW a reinvestigation |
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| Authors: | François Frappier Andrée Marquet |
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| Affiliation: | Laboratoire de Chimie Organique Biologique, Université P.et M. Curie, 4 Place Jussieu, 75230, Paris Cedex 05, France. |
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| Abstract: | [3-14C, 35S]-L-cysteine was tested as precursor of biotin in Achromobacter IVSW. No significant incorporation was observed, in contradiction with the data previously reported. On the other hand, Achromobacter IVSW converts [3H, 14C]-dethiobiotin into biotin. This suggests that biotin is biosynthesized in Achromobacter according to the classical dethiobiotin pathway. |
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