Precious metal economy |
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| Authors: | Merchant Sabeeha S Sagasti Alvaro |
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| Affiliation: | Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, USA. |
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| Abstract: | The zebrafish is emerging as a system of choice for modeling human disease. In this issue of Cell Metabolism, Mendelsohn et al. (2006) describe a model for Menkes disease, a genetic disorder in copper utilization. Using genetic and chemical screens, the authors highlight the impact of maternal nutrition on embryo development. The work reveals a hierarchy of temporal and dosage-dependent phenotypes for copper nutrition. |
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