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Influence of Ca2+ ions on UV-induced damage to mice peritoneal macrophage plasma membranes
Authors:Pirutin S K  Turovetskiĭ V B  Pirutina O V  Kudriashov Iu B
Abstract:It was shown that UV-irradiation caused damage to mice peritoneal macrophage plasma membranes. A decrease in extracellular Ca2+ leads to a decrease of the damaging effect. An increase in extracellular Ca2+ or adding of calcium ionophore A23187 to the medium is accompanied by an increase in a number of damaged cells. These data allow us to suppose that modification of the damaging effect of UV-irradiation by Ca2+ ions can be bound with changing of electric stability of membrane lipid matrix.
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