Pharmacologically relevant proteins |
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| Authors: | Steven E. Ealick Shelly R. Armstrong |
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| Abstract: | The emergence of structure-based drug design as a tool for drug discovery and development has focused increased attention on pharmacologically relevant proteins and the use of their three-dimensional structures to design novel pharmaceutical agents. This review describes recent structural studies of selected macromolecules that have been identified as targets for drug development. Several examples of the successful application of structure-based drug design techniques are also described. |
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