Probabilistic prediction and ranking of human protein-protein interactions |
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Authors: | Michelle S Scott Geoffrey J Barton |
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Institution: | (1) School of Life Sciences Research, College of Life Sciences, University of Dundee, Scotland, UK |
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Abstract: | Background Although the prediction of protein-protein interactions has been extensively investigated for yeast, few such datasets exist
for the far larger proteome in human. Furthermore, it has recently been estimated that the overall average false positive
rate of available computational and high-throughput experimental interaction datasets is as high as 90%. |
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Keywords: | |
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