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Downregulation of calcineurin activity in cervical carcinoma |
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| Authors: | S?Padma,A?Pavani?Sowjanya,Usha?Rani?Poli,Meenakshi?Jain,BN?Rao,Gayatri?Ramakrishna author-information" > author-information__contact u-icon-before" > mailto:gayatri@cdfd.org.in" title=" gayatri@cdfd.org.in" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author |
| Affiliation: | (1) Centre for DNA Fingerprinting and Diagnostics, Nacharam, Hyderabad, A.P, India;(2) M.N.J Institute of Oncology and Regional cancer centre, Hyderabad, A.P, India;(3) Mediciti Hospital, Medchal, A.P, India |
| Abstract: | BackgroundCalcineurin (CaN) is an important serine-threonine phosphatase (PP2B), which plays a crucial role in calcium-calmodulin mediated signal transduction events. Calcineurin has been implicated in pathogenesis of various diseases cardiac hypertrophy, diabetic neuropathy and Alzheimer's, however its role in neoplasia remains unclear. |
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