Adhesion behaviour of murine lymphocytes on the surface of fibrous chitin and its derivatives

Adhesion behaviour of lymphocytes of mouse spleen on the surfaces of chitin and its derivatives was studied. The amount of adhering B lymphocytes was enhanced by the deacetylation of N-acetyl groups and depressed by the introduction of carboxyl groups to the GlcNAc residues of chitin. B lymphocytes have been shown to adhere more effectively to the surface of chitin derivatives than IgG negative cells such as T lymphocytes. However, some morphological change in lymphocyte cells has been observed on adhesion to the basic surface of deacetylated chitin, in spite of little change on neutral or acidic surfaces of chitin derivatives.