| 我国五个地区流行的婴幼儿腹泻轮状病毒的血清型 |
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| 引用本文： | 方肇寅,周长发.我国五个地区流行的婴幼儿腹泻轮状病毒的血清型[J].病毒学报,1989,5(4):393-397. |
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| 作者姓名： | 方肇寅 周长发 |
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| 作者单位： | 中国预防医学科学院病毒学研究所
(方肇寅，温乐英，董虹)，长春市儿童医院
(刘长清，周长发)，大同市卫生防疫站
(王秀珊)，无锡市卫生防疫站
(刘秉辉)，延边医学院
(李玉雨)，秦皇岛市卫生防疫站
(秦树民)，中国预防医学科学院病毒学研究所(洪涛) |
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| 摘 要： |
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| 关 键 词： | 婴幼儿 腹泻 轮状病毒 血清型 |
PREVALENCE OF DIFFERENT ROTAVlRUS SEROTYPES IN INFANTILE GASTROEN-TERITIS IN FIVE REGIONS, CHINA |
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| Fang Zhaoyin Wen Leying Dong Hong Liu Changqing Zhou Guichun Wang Xiushan Liu Binghui Li Yuyu Qin Shumin Hung Tao Institute of Virology,Chinese Academy of Preventive MedicineChangchun Children''''s HospitalHealth and Antiepidemic Station of Datong cityHealth and Antiepiemic Station of Wuxi cityYanbian Medical CollegeHealth and Antiepidemic Station of Qinhuangdao city.PREVALENCE OF DIFFERENT ROTAVlRUS SEROTYPES IN INFANTILE GASTROEN-TERITIS IN FIVE REGIONS, CHINA[J].Chinese Journal of Virology,1989,5(4):393-397. |
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| Authors: | Fang Zhaoyin Wen Leying Dong Hong Liu Changqing Zhou Guichun Wang Xiushan Liu Binghui Li Yuyu Qin Shumin Hung Tao Institute of Virology Chinese Academy of Preventive MedicineChangchun Children's HospitalHealth and Antiepidemic Station of Datong cityHealth and Antiepiemic Station of Wuxi cityYanbian Medical CollegeHealth and Antiepidemic Station of Qinhuangdao city |
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| Abstract: | Human rotaviruses(HRV)in infected stools collected from five regions (Changchun,Yanbian, Datong, Wuxi and Qinhuangdao)during the period 1984-1987 rotavirus seasons were tested for serotype by ELISA using monoclonal Vp7 antibodies and for electropherotype by PAGE. The results showed that serotype 1(79/151) and 2(54/151) strains were predominant in 4 regions in Northern China followed by serotype 3(15/151) and 4 (3/ 151) strains, whereas serotype 3 strain (9/12) seemed to be predominant in Wuxi region in Southern China. The predominant strains in the same region could switch from one serotype to another from year to year. Electro-pherotyping results on 140 HRV strains confirmed that HRV serotype 2 strains were of the short-pattern and serotype 1, 3 and 4 strains were of the long-pattern. These epidemiological data are useful for the design of rotavirus vaccine. |
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| Keywords: | Infantile gastroenteritis Rotavirus Serotype |
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