Growth inhibition activity of thioacetal artemisinin derivatives against human umbilical vein endothelial cells |
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| Authors: | Oh Sangtae Jeong In Howa Shin Woon-Seob Lee Seokjoon |
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| Affiliation: | Department of Chemistry, Yonsei University, Wonju 220-710, South Korea. |
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| Abstract: | Thioacetal artemisinin derivatives, in particular, 10alpha-phenylthiodihydroartemisinins (5), 10beta-benzenesulfonyl-9-epi-dihydroartemisinin (9) and 10alpha-mercaptodihydroartemisinin (11), exhibit good growth inhibition activity against HUVEC proliferation at the concentration level of 1 microM. |
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