Genotoxicity investigation of ELF-magnetic fields in Salmonella typhimurium with the sensitive SOS-based VITOTOX test |
| |
| Authors: | Verschaeve Luc Anthonissen Roel Grudniewska Magda Wudarski Jakub Gevaert Lieven Maes Annemarie |
| |
| Affiliation: | Laboratory of Toxicology, O.D. Public Health and Surveillance, Scientific Institute of Public Health, Brussels, Belgium. luc.verschaeve@wiv-isp.be |
| |
| Abstract: | We performed a genotoxicity investigation of extremely low-frequency (ELF) magnetic fields (MFs, 50 Hz, 100 and 500 μT, 1 and 2 h exposure) alone and in combination with known chemical mutagens using the VITOTOX test. This test is a very sensitive reporter assay of Salmonella typhimurium bacteria based on the SOS response. Our study showed that ELF-MFs do not induce SOS-based mutagenicity in S. typhimurium bacteria and do not show any synergetic effect when combined with chemical mutagens. |
| |
| Keywords: | SOS induction VITOTOX test ELF magnetic fields genotoxicity Salmonella typhimurium |
| 本文献已被 PubMed 等数据库收录！ |
