Human herpesvirus-6 and human herpesvirus-7 (HHV-6, HHV-7) |
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Authors: | Tang Huamin Sadaoka Tomohiko Mori Yasuko |
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Affiliation: | Division of Virology and vaccinology, National Institute of Biomedical Innovation. |
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Abstract: | human herpesvirus 6 (HHV-6) is the major causative agent of exanthem subitum which is one of popular diseases in infant, and establishes latent infections in adults of more than 90%. Recently, the encephalitis caused by reactivated- HHV-6 has been shown in patients after transplantation. In addition, the relationship HHV-6 and drug-induced hypersensitivity syndrome has also been reported. human herpesvirus 7 (HHV-7) was isolated from the stimulated-peripheral blood lymphocytes of a healthy individual, and also causes exanthema subitum. Both viruses are related viruses which belong to betaherpesvirus subfamily, and replicate and produce progeny viruses in T cells. |
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