Preliminary studies on the carcinogenic effects of Penicillium roqueforti toxin (PR toxin) on rats |
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| Authors: | L Polonelli L Lauriola G Morace |
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| Institution: | (1) Istituto di Microbiologia, Università Cattolica del Sacro Cuore, Roma, Italy;(2) Istituto di Anatomia Patologica, Università Cattolica del Sacro Cuore, Roma, Italy |
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| Abstract: | Preliminary results on the carcinogenic activity of a mycotoxin of Penicillium roqueforti (PR toxin) are reported. A squamous epithelioma and a uterine sarcoma were histologically confirmed in 2 of 10 albino rats fed PR toxin in a relatively short time (449 and 551 days respectively). Only an adenocarcinoma was histologically proven within a control group of 10 rats in a significantly longer (931 days) time span. |
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