Ex vivo determination of bone tissue strains for an in vivo mouse tibial loading model |
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Authors: | Alessandra Carriero Lisa Abela Andrew A Pitsillides Sandra J Shefelbine |
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Institution: | 1. Department of Bioengineering, Imperial College London, UK;2. Department of Veterinary Basic Sciences, Royal Veterinary College, London, UK |
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Abstract: | Previous studies introduced the digital image correlation (DIC) as a viable technique for measuring bone strain during loading. In this study, we investigated the sensitivity of a DIC system in determining surface strains in a mouse tibia while loaded in compression through the knee joint. Specifically, we examined the effect of speckle distribution, facet size and overlap, initial vertical alignment of the bone into the loading cups, rotation with respect to cameras, and ex vivo loading configurations on the strain contour maps measured with a DIC system. |
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Keywords: | Bone strain Digital image correlation Mouse Loading Tibia |
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