Changes in the interfacial shear resistance of disc annulus fibrosus from genipin crosslinking |
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| Authors: | Bryan Kirking Thomas Hedman John Criscione |
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| Affiliation: | 1. Orthopeutics LP, 1704 Deepwood Dr, Round Rock, 78681, USA;2. Texas A&M University Department of Biomedical Engineering, USA;3. University of Kentucky, Department of Neurosurgery and Biomedical Engineering, USA |
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| Abstract: | Crosslinking soft tissue has become more common in tissue engineering applications, and recent studies have demonstrated that soft tissue mechanical behavior can be directly altered through crosslinking. Using a recently reported test method that shears adjacent disc lamella, the effect of genipin crosslinking on interlamellar shear resistance was studied using in vitro bovine disc annulus. |
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| Keywords: | Disc Lamella Interfacial shear Lamellar shear Crosslinking Genipin |
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