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Inducible resistance against nisin in Lactobacillus casei
Authors:B Breuer  F Radler
Institution:Institut für Mikrobiologie und Weinforschung, Johannes Gutenberg-Universit?t Mainz, Becherweg 15, D-55099 Mainz, Germany Tel. +49-6131-392662; Fax +49-6131-392695, DE
Abstract:Most strains of Lactobacillus casei tested were found to be nisin-resistant. The addition of nisin to a growing culture of a resistant strain stopped growth for several hours; however, growth then resumed at the previous rate. Nisin induced a resistance mechanism that was lost by one passage in nisin-free medium. During induction with nisin, the cells produced an anionic, phosphate-containing polysaccharide with the subunits rhamnose and galactose. This polysaccharide protected sensitive cells of L. casei against the bactericidal action of nisin. Received: 27 July 1995 / Accepted: 30 October 1995
Keywords:Lactobacillus casei  Nisin  Nisin  resistance  Polysaccharide
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