Inducible resistance against nisin in Lactobacillus casei |
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Authors: | B Breuer F Radler |
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Institution: | Institut für Mikrobiologie und Weinforschung, Johannes Gutenberg-Universit?t Mainz, Becherweg 15, D-55099 Mainz, Germany Tel. +49-6131-392662; Fax +49-6131-392695, DE
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Abstract: | Most strains of Lactobacillus casei tested were found to be nisin-resistant. The addition of nisin to a growing culture of a resistant strain stopped growth
for several hours; however, growth then resumed at the previous rate. Nisin induced a resistance mechanism that was lost by
one passage in nisin-free medium. During induction with nisin, the cells produced an anionic, phosphate-containing polysaccharide
with the subunits rhamnose and galactose. This polysaccharide protected sensitive cells of L. casei against the bactericidal action of nisin.
Received: 27 July 1995 / Accepted: 30 October 1995 |
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Keywords: | Lactobacillus casei Nisin Nisin resistance Polysaccharide |
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