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The naturally occurring biflavonoid, ochnaflavone, inhibits LPS-induced iNOS expression, which is mediated by ERK1/2 via NF-kappaB regulation, in RAW264.7 cells
Authors:Suh Seok-Jong  Chung Tae-Wook  Son Min-Jung  Kim Sung-Hoon  Moon Tae Chul  Son Kun Ho  Kim Hyun Pyo  Chang Hyeun Wook  Kim Cheorl-Ho
Institution:Department of Biological Science, Sungkyunkwan University and National Research Laboratory for Glycobiology, Chunchun-Dong, Jangan-Gu, Suwon City, Kyunggi 440-746, Republic of Korea.
Abstract:
Keywords:Ochnaflavone  iNOS  RAW264  7 cells  NF-κB  Phosphorylation of c-Jun NH2-terminal kinase  IκBα  Inducible nitric oxide synthase  Extracellular signal-regulated kinase  c-Jun NH2-terminal kinase  p38 mitogen-activated protein kinase  Inhibitor κB kinase
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