Glutathione in Tetrahymena thermophila |
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Authors: | B Wagner |
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Affiliation: | Institute of Biochemistry, University of Heidelberg, Federal Republic of Germany. |
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Abstract: | In Tetrahymena, glutathione is synthesized from the same precursors as it is in higher animals and is present in similar intracellular concentrations. The intracellular thiol-disulfide ratio is also identical to that of mammalian tissues, due to the activity of glutathione reductase. The intracellular GSH-level was found to be dependent on the sulfur-containing amino acids in the chemically defined medium. |
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