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Analyses of Pneumocystis Fatty Acids
Authors:EDNA S. KANESHIRO  MELANIET CUSHION  PETER D. WALZER  KOKA JAYASIMHULU
Affiliation:Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221-0006;Veteran's Administration Medical Center and Department of Internal Medicine, Division of Infectious Diseases, Cincinnati, Ohio 45267;Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267
Abstract:The major ester-linked fatty acids of the total lipids extracted from Pneumocystis carinii isolated from the lungs of corticosteroid-trcaicd rats were 16:0. 18:0, 18:1, 18:2 and 20:4. Others detected included 14:0, 16:1 and 22:4. The major sphingolipid fatty acids were 16:0, 18:0,22:0,24:0 and 24:1; others included 14:0, 18:1, 20:0, 23:0, 24:2 and 26:0. The total lipid fatty acid compositions of preparations from appropriate lung controls were similar to those of the organism.
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