Agrobacterium VirE2 gets the VIP1 treatment in plant nuclear import. |
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| Authors: | Doyle V Ward John R Zupan Patricia C Zambryski |
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| Affiliation: | 1. Biology Centre, Institute of Parasitology, Czech Academy of Sciences, České Budějovice (Budweis), Czech Republic;2. Faculty of Science, University of Ostrava, Ostrava, Czech Republic;3. School of Life Sciences, University of Dundee, Dundee, UK;4. School of Applied Sciences, University of Huddersfield, Huddersfield, UK;5. Martsinovsky Institute of Medical Parasitology, Sechenov University, Moscow, Russia;6. Faculty of Sciences, University of South Bohemia, České Budějovice (Budweis), Czech Republic |
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| Abstract: | Agrobacterium tumefaciens transforms plant cells by targeting a large single-stranded DNA molecule (T-strand) to the plant nucleus. The host cell contribution to nuclear import and transformation is the focus of several current articles. Recently, plant proteins have been identified that promote nuclear import of the T-strand. In particular, VIP1 might couple transformation to the importin-dependent nuclear import pathway and deliver the T-strand to chromatin, thereby promoting integration into the host genome. |
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