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Factors Associated with Severe Human Rift Valley Fever in Sangailu,Garissa County,Kenya
Authors:A. Desirée LaBeaud  Sarah Pfeil  Samuel Muiruri  Saidi Dahir  Laura J. Sutherland  Zachary Traylor  Ginny Gildengorin  Eric M. Muchiri  John Morrill  C. J. Peters  Amy G. Hise  James W Kazura  Charles H. King
Abstract:BackgroundMosquito-borne Rift Valley fever virus (RVFV) causes acute, often severe, disease in livestock and humans. To determine the exposure factors and range of symptoms associated with human RVF, we performed a population-based cross-sectional survey in six villages across a 40 km transect in northeastern Kenya.Conclusions/SignificanceOur results demonstrate that a significant proportion of the population in northeastern Kenya has been infected with RVFV. Village and certain animal husbandry activities were associated with more severe disease. Older age, male gender, herder occupation, killing and butchering livestock, and poor visual acuity were useful markers for increased RVFV infection. Formal vision testing may therefore prove to be a helpful, low-technology tool for RVF screening during epidemics in high-risk rural settings.
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