|
|||||
|
|
Antibody formation to morphine and neuromediators in morphinized rats] |
|
| Authors: | S I Tronnikov N B Gamaleia A G Veretinskaia E V Borisova S K Sudakov I P Anokhina |
| Abstract: | The paper demonstrates induction of antibodies to morphine and neurotransmitters (dopamine, norepinephrine, serotonin) in rats treated with intraperitoneal injections of morphine hydrochloride during 2 and 4 weeks in increasing doses. A contribution of such antibodies to the mechanisms of morphine tolerance and formation of physical dependence is considered. |
| Keywords: | |