Identification of nlmTE, the locus encoding the ABC transport system required for export of nonlantibiotic mutacins in Streptococcus mutans |
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| Authors: | Hale John D F Heng Nicholas C K Jack Ralph W Tagg John R |
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| Affiliation: | Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand. |
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| Abstract: | Streptococcus mutans UA159, the genome sequence reference strain, exhibits nonlantibiotic bacteriocin (mutacin) activity. In this study, we have combined bioinformatic and mutational analyses to identify the ABC transporter designated NlmTE, which is required for mutacin biogenesis in strain UA159 as well as in another mutacin producer, S. mutans N. |
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