Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYC |
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| Authors: | Wong Jeffrey V Yao Guang Nevins Joseph R You Lingchong |
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| Institution: | Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. |
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| Abstract: |  Download : Download high-res image (249KB)Download : Download full-size imageHighlights? Gene expression noise is an efficient means to probe dose responses ? Variability in MYC reveals biphasic E2f1 dose response ? Modeling predicts serum attenuates E2F repression by MYC ? Biphasic expression underlies discrimination of aberrant levels of growth signaling |
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