| 载药脂质体的研究与应用进展 |
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| 引用本文： | 杨静,周绍兵.载药脂质体的研究与应用进展[J].现代生物医学进展,2007,7(10):1597-1600. |
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| 作者姓名： | 杨静 周绍兵 |
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| 作者单位： | 西南交通大学材料科学与工程学院,材料先进技术教育部重点实验室,成都,610031 |
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| 摘 要： | 载药脂质体给药系统已成为国内外的研究热点。传统脂质体经修饰和改良后表现出良好的生物相容性,缓释性和靶向性。新型脂质体在经皮给药,肺部给药,脑部靶向治疗,基因治疗等方面的应用研究结果显示,集药物缓释、靶向于一体的具有良好生物安全性的脂质体给药系统具有很大发展潜力。本文综述了该领域中的最新研究进展。
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| 关 键 词： | 脂质体 药物载体 缓释 靶向 |
| 文章编号： | 1673-6273（2007）10-1597-04 |
| 修稿时间： | 2007-05-28 |
Progress in Research and Application of Liposome |
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| YANG Jing,ZHOU Shao-bing.Progress in Research and Application of Liposome[J].Progress in Modern Biomedicine,2007,7(10):1597-1600. |
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| Authors: | YANG Jing ZHOU Shao-bing |
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| Institution: | Key Laboratory of Advanced Technologies of Materials, School of Materials Science and Engineering, Southwest Jiaotong University, ChengDu 610031, China |
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| Abstract: | The application of liposome as a drug deliver system has become research hot topic at home and abroad.The lipo- some appears good biocompatibility,slow-releasing potential and targeting property after chemical or physical modification and improve- ment.The applications of liposome in trans-dermal drug delivery system,pulmonary drug delivery system,brain targeted thereby and gene therapy indicated that liposome drug delivery system will has great development potential for its good biocompatibility,slow-releas- ing potential and targeting property.The latest advancement in liposome research was reviewed in this paper. |
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| Keywords: | liposome drug carrier sustained drug release targeting |
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