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The Epidemiology of Mould Infections in Argentina: Review and Experience |
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| Authors: | María Cecilia Dignani Graciela Davel Nicolás Refojo Mariana Mazza Susana Córdoba Alejandra Inés Hevia Rubén Antonio Abrantes Guillermina Isla Julián Fernández María Cristina Rivas Alejandra Valledor Ana Laborde María Laura Pereyra Inés Roccia Rossi |
| Institution: | 1. Registro Micosis Invasoras (REMIIN), Yerbal 315, App 2B., C1405CDG, Ciudad Aut??noma de Buenos Aires (CABA), Argentina 2. Departamento Micolog??a, INEI (Instituto Nacional de Enfermedades Infecciosas) ??Dr. C. G. Malbr??n?? ANLIS (Administraci??n Nacional de Laboratorios e Instituto de Salud), Av. V??lez Sarsfield 563, C1282AFF, CABA, Argentina 3. Hospital Italiano, Juan D. Per??n 4190, C1181ACH, CABA, Argentina 4. Fundaleu (Fundaci??n de Lucha contra la Leucemia), Uriburu 1450, C1114AAN, CABA, Argentina 5. Hospital Universitario Austral, Av. Pte. Per??n 1500, B1629ODT, Pilar, Bs. As., Argentina 6. Hospital Gral. San Mart??n, Av. 1, 1791, B1904CFH, La Plata, Bs. As., Argentina |
| Abstract: | During the last decades, there has been an increasing proportion of patients susceptible to invasive fungal disease (IFD). The epidemiology of IFD varies mainly due to geography, antifungal exposure, and nosocomial reservoirs. We reviewed the Argentinean epidemiology of invasive mold disease (IMD) by analyzing laboratory and clinical data. Invasive mold disease was the second most prevalent IFD following the yeasts, with a prevalence that ranged from 0.98 to 1.31/100,000 population. The majority (60?C85?%) of IMD was caused by hyalohyphomycetes followed by Mucorales (6?C21?%) and phaeohyphomycetes (7?C13?%). The most prevalent genera were Aspergillus (40?C67?% of IMD) followed by Fusarium (10?C14?%). The most prevalent species were A. fumigatus (38?C50?%) followed by A. flavus (27?C43?%). In immunocompromised patients in Argentina the most prevalent agents of IMD are Aspergillus, followed by Fusarium and Mucorales, while the most prevalent Aspergillus species are A. fumigatus followed by A. flavus. |
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